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VIP

Vasoactive intestinal peptide, also known as vasoactive intestinal polypeptide or VIP, is a peptide hormone that is vasoactive in the intestine. VIP is a peptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, the ligand of class II G protein–coupled receptors. VIP is produced in many tissues of vertebrates including the gut, pancreas, and suprachiasmatic nuclei of the hypothalamus in the brain. VIP stimulates contractility in the heart, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. In humans, the vasoactive intestinal peptide is encoded by the VIP gene.

 
VIP has a half-life (t½) in the blood of about two minutes.
Catalog No. Peptide Name Sequence Purity
P80083Hu1 VIP, Human HSDAVFTDNYTRLRKQMAVKKYLNSILN-NH2 > 98%
P80083Po1 VIP, Porcine HSDAVFTDNYTRLRKQMAVKKYLNSILN-NH2 > 98%
P80083Ra1 VIP, Rat HSDAVFTDNYTRLRKQMAVKKYLNSILN-NH2 > 98%
P80083Ov1 VIP, Ovine HSDAVFTDNYTRLRKQMAVKKYLNSILN-NH2 > 98%
P80083Pe1 [Tyr1,DPhe2] GHRF (1-29), N-Acetyl, amide Ac-Y-DPhe-DAIFTNSYRKVLGQLSARKLLQDIMSR-NH... > 98%
P80083Ra2 PHI, Rat HADGVFTSDYSRLLGQISAKKYLESLI-NH2 > 98%
P80083Ca1 VIP, Cavia HSDALFTDTYTRLRKQMAMKKYLNSVLN-NH2 > 98%
P80083Pe2 [(4Cl)DPhe6,Leu17] VIP HSDAV-(pCl)DPhe-TDNYTRLRKQLAVKKYLNSILN-N... > 98%

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