Secretin | | Other Peptide

Secretin

Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by regulating secretions in the stomach, pancreas, and liver. It is a peptide hormone produced in the S cells of the duodenum, which are located in the intestinal glands. In humans, the secretin peptide is encoded by the SCT gene.

Secretin helps regulate the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate from the ductal cells of the pancreas. It also stimulates bile production by the liver; the bile emulsifies dietary fats in the duodenum so that pancreatic lipase can act upon them. Meanwhile, in concert with secretin's actions, the other main hormone simultaneously issued by the duodenum, cholecystokinin, is stimulating the gallbladder to contract, delivering its stored bile for the same reason.

Catalog No.	Peptide Name	Sequence	Purity
P80075Hu1	Secretin, Human	HSDGTFTSELSRLREGARLQRLLQGLV-NH2	> 98%
P80075Po1	Secretin (5-27), Porcine	TFTSELSRLRDSARLQRLLQGLV-NH2	> 98%
P80075Po2	Secretin, Porcine	HSDGTFTSELSRLRDSARLQRLLQGLV-NH2	> 98%
P80075Ra1	Secretin, Rat	HSDGTFTSELSRLQDSARLQRLLQGLV-NH2	> 98%

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