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Renin Substrate & Inhibitor

Renin inhibitors are a group of pharmaceutical drugs used primarily in treatment of essential hypertension (high blood pressure).

 
These drugs inhibit the first and rate-limiting step of the renin–angiotensin–aldosterone system (RAAS), namely the conversion of angiotensinogen to angiotensin I. This leads to a totality in absence of Angiotensin II based on the rationale that renin only acts to inhibit this step unlike Angiotensin Converting Enzyme which is also involved in other biochemical reactions. 
Catalog No. Peptide Name Sequence Purity
P80074Pe1 P-H-P-F-H-F-F-V-Y-K PHPFHFFVYK > 98%
P80074Hu1 Acetyl, Angiotensinogen (1-14), Human Ac-DRVYIHPFHLVIHN > 98%
P80074Hu2 Angiotensinogen (1-13), Human DRVYIHPFHLVIH > 98%
P80074Po1 Angiotensinogen (1-14), Porcine DRVYIHPFHLLVYS > 98%
P80074Hu3 Angiotensinogen (1-14), Human DRVYIHPFHLVIHN > 98%
P80074Po2 Acetyl Angiotensinogen (1-14), Porcine Ac-DRVYIHPFHLLVYS > 98%
P80074Ra1 [Val8] Renin Substrate Tetradecapeptide, Rat DRVYIHPVHLLYYS > 98%
P80074Ra2 [Cys8] Renin Substrate Tetradecapeptide, Rat DRVYIHPCHLLYYS > 98%
P80074Ra3 Renin Substrate Tetradecapeptide, Rat DRVYIHPFHLLYYS > 98%
P80074Ra4 [Leu8] Renin Substrate Tetradecapeptide, Rat DRVYIHPLHLLYYS > 98%

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