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LHRH (GnRH) Antagonist

Gonadotropin-releasing hormone antagonists (GnRH antagonists) are a class of medications that antagonize the gonadotropin-releasing hormone receptor (GnRH receptor) and thus the action of gonadotropin-releasing hormone (GnRH).

Some GnRH antagonists are similar in structure to natural GnRH (a hormone made by neurons in the hypothalamus) but that have an antagonistic effect. These GnRH antagonists are peptide molecules that are made up multiple, often synthetically produced amino acids. Others are small-molecule, non-peptide compounds. GnRH antagonists compete with natural GnRH for binding to GnRH receptors, thus decreasing or blocking GnRH action in the body.

Catalog No.	Peptide Name	Sequence	Purity
P80145Pe1	Goserelin, free base	Pyr-HWSY-D-Ser(tBu)-LRP-Azagly-NH2	> 98%
P80145Pe2	Luteinizing Hormone-Releasing Hormone Antagonist	Ac-D-2-Nal-p-chloro-D-F-β-(3-pyridyl)-D...	> 98%
P80145Ga1	LHRH, Gallus	Pyr-HWSYGLQPG-NH2Trifluoroacetate salt	> 98%
P80145Pe3	Acetyl-(D-Trp1,4-chloro-D-Phe2,D-Trp3,D-Arg6,D-Ala10)-LHRH	Ac-D-W-4-chloro-D-F-D-WSY-D-RLRP-D-A-NH2	> 98%
P80145Pe4	Histrelin Acetate	Pyr-HWSY-D-His(Bzl)-LRP-NHEtAcetate salt	> 98%
P80145Pe5	Buserelin(NHNH2)	Pyr-HWSY-D-Ser(tBu)-LRP-NHNH2Trifluoroac...	> 98%
P80145Pe6	Deslorelin High acetate salt	Pyr-HWSY-D-WLRP-NHEt High acetate salt	> 98%
P80145Pe7	Cetrorelix	Ac-D-2-Nal-4-chloro-D-F-β-(3-pyridyl)-D...	> 98%
P80145Pe8	Nafarelin	Pyr-HWSY-D-2-Nal-LRPG-NH2Acetate salt	> 98%
P80145Pe9	LHRH II	Pyr-HWSHGWYPG-NH2Trifluoroacetate salt	> 98%
P80145Pe10	Goserelin	Pyr-HWSY-D-Ser(tBu)-LRP-Azagly-NH2Acetat...	> 98%

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