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Histone Related Substrate

In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and playing a role in gene regulation. Without histones, the unwound DNA in chromosomes would be very long (a length to width ratio of more than 10 million to 1 in human DNA). For example, each human diploid cell (containing 23 pairs of chromosomes) has about 1.8 meters of DNA; wound on the histones, the diploid cell has about 90 micrometers (0.09 mm) of chromatin. When the diploid cells are duplicated and condensed during mitosis, the result is about 120 micrometers of chromosomes.

Catalog No.	Peptide Name	Sequence	Purity
P80124Pe1	CDK5 Substrate [PK-pT-PKKAKKL], Phosphorylated	PK-pT-PKKAKKL	> 98%
P80124Pe2	AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA]	ARKRERTYSFGHHA	> 98%
P80124Pe3	CDK5 Substrate [PKTPKKAKKL]	PKTPKKAKKL	> 98%
P80124Pe4	CDK5 Substrate [PKTPKKAKKL], Biotinylated	Biotin-PKTPKKAKKL	> 98%
P80124Pe5	AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTY-pS-FGHHA], Phosphorylated	ARKRERTY-pS-FGHHA	> 98%

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