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Endothelins & Related Peptide

Endothelins are peptides with receptors and effects in many body organs. Endothelin constricts blood vessels and raises blood pressure. The endothelins are normally kept in balance by other mechanisms, but when overexpressed, they contribute to high blood pressure (hypertension), heart disease, and potentially other diseases.

Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, lungs, kidneys, and brain.[4][5] As of 2018, endothelins remain under extensive basic and clinical research to define their roles in several organ systems.

Catalog No.	Peptide Name	Sequence	Purity
P80034Pe1	IRL-1720	Ac-DKEAVYFAHLDIIW	> 98%
P80034Hu1	Endothelin-3, Human	CTCFTYKDKECVYYCHLDII-Trp(Cys1&Cys15 brid...	> 98%
P80034Hu2	Endothelin-2, Human	CSCSSWLDKECVYFCHLDII-Trp(Cys1&Cys15 brid...	> 98%
P80034Hu3	Big Endothelin-1 (1-38), Human	CSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSPR-Se...	> 98%
P80034Pe2	BQ-123	cyclo(DTrp-DAsp-P-DVal-Leu)	> 98%
P80034Pe3	Vasoactive Intestinal Contractor [VIC]	CSCNSWLDKECVYFCHLDII-Trp(Cys1&Cys15 brid...	> 98%
P80034Hu4	Endothelin-1, Human	CSCSSLMDKECVYFCHLDII-Trp (Cys1&Cys15 bri...	> 98%

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